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Kang-Yell Choi


Kang-Yell Choi

Yonsei University, South Korea

Biography

Kang-Yell Choi finished his doctorate in Biochemistry at the Purdue University in 1993, and performed research related with cell signaling with the yeast pheromone signaling pathway as a model system at Harvard Medical School as a postdoctoral fellow.  There, he characterized Saccharomyces Ste5 functioning at the MAP kinase pathway as a 1st protein introduced concept for the "Scaffold Protein" in the community.  In 1995, he returned back to Korea as a professor of Yonsei University. Since then, he has been working on mammalian cell signaling related with several different pathophysiologies such as growth control of cells and human cancer.   He is serving as the chief of the National Research Laboratory of the Molecular Complex Control for recent 5 years, and currently positioned as the Director of the Translational Research Center for Protein Function Control supported by Ministry of Science, ICT and Future Panning of Korea.

Abstract

Abstract : Degradation of both β-catenin and RAS via targeting the Wnt/β-catenin pathway is an ideal approach for colorectal cancer treatment